HUNTINGTON’S DISEASE CLINICAL RESEARCH

INFORMATION FOR PATIENTS, RELATIVES AND CARERS

Sarah Tabrizi PhD FRCP

Professor of Clinical Neurology

This site aims to bring together information about clinical research projects in Huntington’s disease (HD) for patients, carriers of the HD genegene. The sequence of DNA that tells a cell how to make a protein

Clinical research in Huntington’s disease is entering a new era. We are already running clinical trials into treatments that may slow down progression of the disease. There are many new treatments that have been shown to be effective in animal models of HD and are waiting to be tested in humans.

Through the Huntington’s Disease Multidisciplinary Clinic of the National Hospital for Neurology and Neurosurgery, we are already running a number of studies to determine the best measures of disease progression and expect to be in the front line when human treatment trials begin in earnest.

Definitions of words and phrases are underlined in purpledefinition: underlined in purple.

To navigate the site, choose one of the links on the left, move your mouse pointer over them and a definition will pop up.

Latest news

11th January, 2010 - Euro-HD Network newsletter December 2009

The December 2009 newsletter has recently been published by the Euro-HD network .

You can download current and past newsletters from the EHDN site (see right side of this page under ‘Latest news of the network’)

EHDN is a Europe-wide collaboration of HD researchers sharing information and ideas about HD, clinical studies and possible treatments.

EHDN is important for our research here at UCL Institute of Neurology, particularly the REGISTRY and TRACK-HD projects.

24th September, 2009 - Research update

We have updated our Global Research page to include the very latest news from round the world on the development of treatments for HD.

7th September, 2009 - Latest EHDN newsletter includes article about TRACK-HD

The Euro-HD network March 2009 newsletter has been released. It includes an interesting article written by a male HD gene carrier participating in TRACK-HD here at UCL. You can download the newsletter from the EHDN site. EHDN is a Europe-wide collaboration of HD researchers sharing information and ideas about HD, studies and possible treatments. EHDN is important for our research here at UCL, particularly the REGISTRY and TRACK-HD projects.

14th July, 2008 - A new inflammatory pathway in HD

I am pleased to announce a major new paper published in a top scientific publication, The Journal of Experimental Medicine. Our findings have highlighted a new pathway by which HD may cause damage and may open up new avenues of possible future therapies for HD. Read more on our new HD Inflammation page.

12th July, 2008 - Meet the team

You can now find out about members of our HD clinical research team and their research interests on the new HD research team page.

7th July, 2008 - Download our HD therapies update leaflet

We have prepared a printable leaflet giving accessible information on forthcoming possible therapies for HD that researchers round the world are working on. You can download it from our Global update page.

4th July, 2008 - A new study publication

A new paper reporting the results of our research has been published in the journal Neuropsychologia. The paper arose from the ICE-HD study and is entitled Defective emotion recognition in early HD is neuropsychologically and anatomically generic. See the Our results page for details.

21st March, 2008 - Research Update

We have updated our Global Research page to include the very latest news from round the world on the development of treatments for HD.

28th February, 2008 - EHDN newsletter

The Euro-HD network December 2009 newsletter has been released. You can download it from the EHDN website.

EHDN is a Europe-wide collaboration of HD researchers sharing information and ideas about HD, studies and possible treatments. EHDN is important for our research here at UCL, particularly the REGISTRY and TRACK-HD projects.

22nd February, 2008 - Global Research Update

We have updated our Global Research page to include the very latest news from round the world on the development of treatments for HD.